Glicentin is a 69 amino acid peptide produced by the post translational processing of pro-glucagon in the intestines.  Regul Pept. 1981 May;2(2):139-50.  The other proglucagon (PG)-derived peptides include  glucagon-like peptide-1, glucagon-like peptide-2 and Oxyntomodulin.  Glicentin is secreted from L cells in the gut along with GLP-1 and GLP-2.   Endocrinology. 1986 Oct;119(4):1467-75. Glicentin has also been demonstrated in the hypothalamus and brainstem. No Glicentin receptors have been identified yet.  Glicentin is excreted after metabolism in the kidney   Am J Physiol. 1986 May;250(5 Pt 1):E545-50.   such that levels are raised in uraemic patients .  J Clin Endocrinol Metab. 1992 Feb;74(2):379-84.   Glicentin seems to stimulate growth of normal and atrophic small bowel mucosa, through mechanisms independent of luminal factors as well as indirectly through stimulation of luminal secretions. J Pediatr Surg. 2003 Apr;38(4):579-84.  Glicentin may have a role in stimulation of gastric and pancreatic (insulin) secretions as well as in regulation of gut motility. 

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